US Patent Issued to The Broad Institute, The Brigham and Women's Hospital on Nov. 4 for "Inhibitors of RNA-guided nuclease activity and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,244, issued on Nov. 4, was assigned to The Broad Institute Inc. (Cambridge, Mass.) and The Brigham and Women's Hospital Inc. (Boston).

"Inhibitors of RNA-guided nuclease activity and uses thereof" was invented by Amit Choudhary (Boston) and Kurt Cox (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for the inhibition of the function of RNA guided endonucleases, including the identification and use of such inhibitors. Methods of identifying inhibitor compounds of RNA guided nucleases, assays for detecting nuclease activity and compounds for use therein are also provided."

The patent was filed on Au...