ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,447, issued on Sept. 9, was assigned to The Broad Institute Inc. (Cambridge, Mass.), President and Fellows of Harvard College (Cambridge, Mass.) and Massachusetts Institute of Technology (Cambridge, Mass.).
"Engineered muscle targeting compositions" was invented by Pardis Sabeti (Cambridge, Mass.), Mohammadsharif Tabebordbar (Cambridge, Mass.) and Simon Ye (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are targeting moieties that can be capable of specifically targeting muscle cells and can include an n-mer motif. In some embodiments, the n-mer motif contains an RGD motif. Also described herein are vector systems,...