US Patent Issued to THE BROAD INSTITUTE, Massachusetts Institute of Technology on March 25 for "Cas proteins with reduced immunogenicity and methods of screening thereof" (Massachusetts Inventor)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,594, issued on March 25, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.) and Massachusetts Institute of Technology (Cambridge, Mass.).

"Cas proteins with reduced immunogenicity and methods of screening thereof" was invented by Feng Zhang (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure generally relates to systems, methods and compositions related to Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and components thereof. The present disclosure also relates to methods, systems, and compostions modified to reduce immunogenicity. Additionally, the present disclosure relates to metho...