ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,450, issued on March 18, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.), Massachusetts Institute of Technology (Cambridge, Mass.) and THE ROCKEFELLER UNIVERSITY (New York).

"Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for HBV and viral diseases and disorders" was invented by Sangeeta Bhatia (Cambridge, Mass.), Charles Rice (New York), Feng Zhang (Cambridge, Mass.), David Benjamin Turitz Cox (Cambridge, Mass.), Vyas Ramanan (Cambridge, Mass.), Robert Schwartz (Cambridge, Mass.) and Amir Shlomai (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides for delivery, engineer...