US Patent Issued to THE BROAD INSTITUTE, Massachusetts Institute of Technology, PRESIDENT AND FELLOWS OF HARVARD COLLEGE on Oct. 7 for "CRISPR having or associated with destabilization domains" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,320, issued on Oct. 7, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.), Massachusetts Institute of Technology (Cambridge, Mass.) and PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Mass.).

"CRISPR having or associated with destabilization domains" was invented by Feng Zhang (Cambridge, Mass.), Bernd Zetsche (Cambridge, Mass.) and Amit Choudhary (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure includes non-naturally occurring or engineered CRISPR Cas9, each associated with at least one destabilization domain (DD), along with compositions, systems and complexes involving the DD-CRISPR Cas9, nucleic acid m...