US Patent Issued to THE BROAD INSTITUTE, MASSACHUSETTS INSTIT JTE OF TECHNOLOGY, UNIVERSITY OF TOKYO, PRESIDENT AND FELLOWS OF HARVARD COLLEGE on March 25 for "Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems" (Japanese, American Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,595, issued on March 25, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.), MASSACHUSETTS INSTIT JTE OF TECHNOLOGY (Cambridge, Mass.), UNIVERSITY OF TOKYO (Tokyo) and PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Mass.).

"Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems" was invented by Silvana Konermann (Cambridge, Mass.), Alexandro Trevino (Cambridge, Mass.), Mark Brigham (Cambridge, Mass.), Fei Ran (Cambridge, Mass.), Patrick Hsu (Cambridge, Mass.), Chie-Yu Lin (Cambridge, Mass.), Osamu Nureki (Tokyo), Hiroshi Nishimasu (Tokyo), Ryuichiro Ishitani (Tokyo) and Feng Zhang (Cambridge, Mass.).

According to t...