US Patent Issued to The Broad Institute, Dana-Farber Cancer Institute, The General Hospital on Oct. 7 for "Methods for profiling the T-cell-receptor repertoire" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,372, issued on Oct. 7, was assigned to The Broad Institute Inc. (Cambridge, Mass.), Dana-Farber Cancer Institute Inc. (Boston) and The General Hospital Corp. (Boston).

"Methods for profiling the T-cell-receptor repertoire" was invented by Nir Hacohen (Brookline, Mass.), Catherine Ju-Ying Wu (Brookline, Mass.), Edward F. Fritsch (Concord, Mass.) and Ute E. Burkhardt (Belmont, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to methods for profiling subject specific and personalized T cell receptor (TCR) repertoires using a single-cell sequencing method. More particularly, disclosed are methods for determining binding...