US Patent Issued to THE BROAD INSTITUTE, DANA-FARBER CANCER INSTITUTE, INSTITUTO CARLOS SLIM DE LA SALUD A.C. on May 27 for "Tepoxalin targeting of ABCB1 overexpressing cancers" (Massachusetts Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,313,632, issued on May 27, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.), DANA-FARBER CANCER INSTITUTE INC. (Boston) and INSTITUTO CARLOS SLIM DE LA SALUD A.C. (Mexico City).

"Tepoxalin targeting of ABCB1 overexpressing cancers" was invented by Steven Corsello (Boston), Ryan Spangler (Cambridge, Mass.), Rohith Nagari (Cambridge, Mass.) and Todd Golub (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions and methods for the diagnosis and treatment or prevention of cancers that exhibit elevated expression and/or amplification of the ABCB1 (MDR1) transporter, optionally for reasons rel...