US Patent Issued to The Brigham and Women's Hospital on Sept. 30 for "Inhibitors of macrophage migration inhibitory factor" (Russian, American Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,417, issued on Sept. 30, was assigned to The Brigham and Women's Hospital Inc. (Boston).

"Inhibitors of macrophage migration inhibitory factor" was invented by Mihaela Gadjeva (Cambridge, Mass.), Nikolay E. Nifantiev (Moscow) and Igor V. Zavarzin (Moscow).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides a compound of Formula (I): [Formula I] or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, W, L, R8, and R9 are as described herein. Pharmaceutical compositions including these compounds and methods of using these compounds for treating parasitic infections (e.g., malaria), cancer, cardiovascu...