US Patent Issued to The Brigham and Women's Hospital on Nov. 25 for "Co-delivery of nucleic acids for simultaneous suppression and expression of target genes" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,589, issued on Nov. 25, was assigned to The Brigham and Women's Hospital Inc. (Boston).

"Co-delivery of nucleic acids for simultaneous suppression and expression of target genes" was invented by Omid Farokhzad (Waban, Mass.), Xiaoding Xu (Malden, Mass.) and Jinjun Shi (Newton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Nanoparticulate pharmaceutical formulations and methods for co-delivery of two or more species of nucleic acids for simultaneous suppression and expression of target genes in a cell, are provided. The nanoparticles encapsulate two or more nucleic acid species. The first nucleic acid suppresses expression of a gene or product...