US Patent Issued to The Board of Trustees of the University of Illinois on June 17 for "Recombinant herpes simplex virus for cancer immunotherapy" (Illinois Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,794, issued on June 17, was assigned to The Board of Trustees of the University of Illinois (Urbana, Ill.).

"Recombinant herpes simplex virus for cancer immunotherapy" was invented by Bin He (Chicago) and Xing Liu (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for treating a subject with cancer by administering to the subject a therapeutically effective amount of a recombinant Herpes Simplex Virus-1 (HSV-1) that expresses only a C-terminal portion of Gamma134.5 protein (e.g., amino acid residues 147-263) with no wild-type or intact Gamma134.5 protein expression is provided. The recombinant HSV-1 of this invention instigates immune ...