US Patent Issued to The Board of Trustees of the Leland Stanford Junior University on Sept. 9 for "Interferon-gamma biased agonists" (California, Illinois Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,226, issued on Sept. 9, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Interferon-gamma biased agonists" was invented by Kenan Christopher Garcia (Menlo Park, Calif.) and Juan Luis Mendoza (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are compositions and methods for modulating IFN-Gamma-mediated signaling by completely or partially agonizing the downstream signal transduction mediated through at least one of the IFN-Gamma receptors. More particularly, the disclosure provides novel IFN-Gamma polypeptide variants with reduced binding affinity to at least one of its recep...