US Patent Issued to The Board of Trustees of the Leland Stanford Junior University on Sept. 16 for "Synthetic miniature Crispr-Cas (CasMINI) system for eukaryotic genome engineering" (California Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,994, issued on Sept. 16, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Synthetic miniature Crispr-Cas (CasMINI) system for eukaryotic genome engineering" was invented by Lei S. Qi (Stanford, Calif.) and Xiaoshu Xu (Stanford, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are Cas proteins and guide RNA molecules engineered to exhibit increased activity in eukaryotic cells. The provided Cas proteins and RNA molecules are particularly useful for applications where modulation of eukaryotic nucleic acids with relatively small molecules is advantageous. Also provided are nucleic...