ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,579, issued on Oct. 28, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).
"Compositions and methods for inhibiting T cell exhaustion" was invented by Crystal Mackall (Stanford, Calif.), Rachel Lynn (Redwood City, Calif.), Evan Weber (Redwood City, Calif.) and Elena Sotillo (Redwood City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to T cell compositions and methods of using the same in the context of therapy and treatment. In particular, the invention provides T cells that are modified (e.g., genetically and/or functionally) to maintain functionality under condi...