US Patent Issued to The Board of Trustees of the Leland Stanford Junior University on Nov. 11 for "Recombinant adeno-associated virus capsids with enhanced human pancreatic tropism" (California Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,467,065, issued on Nov. 11, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Recombinant adeno-associated virus capsids with enhanced human pancreatic tropism" was invented by Katja Pekrun (Palo Alto, Calif.) and Mark A. Kay (Los Altos, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to variant AAV capsid polypeptides, wherein the variant AAV capsid polypeptides exhibit increased transduction and/or tropism in human pancreatic tissue or human islets as compared non-variant parent capsid polypeptides."

The patent was filed on Dec. 6, 2022, under Application No. 18/062...