ALEXANDRIA, Va., June 16 -- United States Patent no. 12,303,475, issued on May 20, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Conditioning irradiated tissue for increasing vascularity" was invented by Derrick C. Wan (Stanford, Calif.), Geoffrey C. Gurtner (Portola Valley, Calif.) and Michael T. Longaker (Atherton, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods of increasing perfusion and vascularity in irradiated tissue and of increasing retention of fat cells in a fat graft in irradiated tissue by applying an effective amount of DFO to the irradiated tissue at a treatment site. The DFO may be administered transdermally."

The patent was...