US Patent Issued to The Board of Trustees of the Leland Stanford Junior University on Dec. 16 for "Neuroprotection of neuronal soma and axon by modulating ER stress/UPR molecules" (California Inventor)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,356, issued on Dec. 16, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Neuroprotection of neuronal soma and axon by modulating ER stress/UPR molecules" was invented by Yang Hu (Palo Alto, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for treating a mammalian subject for an optic nerve (ON) neuropathy and/or reducing or ameliorating degeneration of axons and/or soma of RGCs are provided. Aspects of the composition include a mammalian viral vector, comprising a murine Gamma-synuclein promoter, or functional fragment thereof, that promotes expression of a transgene sp...