ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,464, issued on March 18, was assigned to The Board of Regents of The University of Texas System (Austin, Texas).
"Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids" was invented by Daniel J. Siegwart (Dallas) and Jason B. Miller (Dallas).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides one or more amino lipids such as an amino lipids containing a sulfonic acid or sulfonic acid derivative of the formulas:wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to...