US Patent Issued to The Board of Regents of The University of Texas System on July 15 for "Lipid nanoparticle compositions for delivery of mRNA and long nucleic acids" (Texas Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,580, issued on July 15, was assigned to The Board of Regents of The University of Texas System (Austin, Texas).

"Lipid nanoparticle compositions for delivery of mRNA and long nucleic acids" was invented by Daniel J. Siegwart (Dallas) and Qiang Cheng (Dallas).

According to the abstract* released by the U.S. Patent & Trademark Office: "In some aspects, the present disclosure provides compositions of lipid nanoparticles useful for the delivery of large RNAs including mRNAs. These compositions may include a cationic ionizable lipid, a phospholipid, a PEGylated lipid, and a steroid including using less of a cationic ionizable lipid than compositions with shorter nucleic acids. These c...