ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,657, issued on Aug. 19, was assigned to The Board of Regents of the University of Texas System (Austin, Texas) and UNIVERSITY OF PALERMO (Palermo, Italy).

"Small molecules that bind and/or modulate differentforms of tau oligomers" was invented by Rakez Kayed (Galveston, Texas), Filippa Lo Cascio (Sicily, Italy), Antonio Palumbo Piccionello (Sicily, Italy) and Andrea Pace (Sicily, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to novel small molecules of Formulas I, II, III, Ilia, Illb, and IV and pharmaceutically acceptable salts thereof, as well as the preparation and the use thereof."

The patent was filed on Ap...