US Patent Issued to The Administrators of the Tulane Educational Fund on June 24 for "Mutated e. coli enterotoxins as anti-inflammatory agents" (Louisiana, Alabama Inventors)

ALEXANDRIA, Va., June 25 -- United States Patent no. 12,337,025, issued on June 24, was assigned to The Administrators of the Tulane Educational Fund (New Orleans).

"Mutated e. coli enterotoxins as anti-inflammatory agents" was invented by Elizabeth Bray Norton (New Orleans) and John David Clements (Dadeville, Ala.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides compositions and methods for reducing symptoms of inflammation by administering therapeutically effective amounts of (a) (1) enterotoxic E. coli heat labile detoxified toxin A subunit that interferes with the function of ADP-ribosylation factor and inhibits ADP-ribosylation, or (2) A1 subunit that interferes with the function of...