US Patent Issued to Temple University-of the Commonwealth System of Higher Education on March 18 for "Methods and compositions for RNA-guided treatment of HIV infection" (Pennsylvania, New Jersey Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,429, issued on March 18, was assigned to Temple University-of the Commonwealth System of Higher Education (Philadelphia).

"Methods and compositions for RNA-guided treatment of HIV infection" was invented by Kamel Khalili (Bala Cynwyd, Pa.), Wenhui Hu (Cherry Hill, N.J.) and Yonggang Zhang (Maple Shade, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions for specifically cleaving target sequences in retroviruses include nucleic acids encoding a Clustered Regularly Interspace Short Palindromic Repeat (CRISPR) associated endonuclease and a guide RNA sequence complementary to one or more target nucleic acid sequences in a retrovirus genome...