US Patent Issued to Southern Methodist University on Jan. 28 for "Mechanosynthesis of a co-amorphous formulation of creatine with citric acid and humidity-mediated transformation into a co-crystal" (Texas Inventors)

ALEXANDRIA, Va., Jan. 29 -- United States Patent no. 12,208,076, issued on Jan. 28, was assigned to Southern Methodist University (Dallas).

"Mechanosynthesis of a co-amorphous formulation of creatine with citric acid and humidity-mediated transformation into a co-crystal" was invented by Tomche Runchevski (Dallas), Kyle B. Pekar (Corpus Christi, Texas) and Jonathan B. Lefton (Fort Worth, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes a co-crystal of creatine and citric acid obtained by milling, methods of making the same that include a process for the preparation of co-amorphous formulation of creatine and citric acid, the process comprising: mixing creatine and citric ac...