US Patent Issued to SOUTH DAKOTA BOARD OF REGENTS on April 22 for "Vasoactive topical compound to affect tissue blood flow, reduce tissue necrosis and promote healing" (South Dakota Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,057, issued on April 22, was assigned to SOUTH DAKOTA BOARD OF REGENTS (Pierre, S.D.).

"Vasoactive topical compound to affect tissue blood flow, reduce tissue necrosis and promote healing" was invented by Hunter Moyer (Rapid City, S.D.) and Daniel Heglund (Rapid City, S.D.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions and systems for improving tissue perfusion such that blood flow is increased, improving tissue healing time and reducing or eliminating tissue necrosis. In a preferred embodiment, the compositions comprise a phosphodiesterase inhibitor, a calcium channel blocker, a nitric oxide producer, a...