ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,542, issued on March 18, was assigned to Shihuida Pharmaceutical Group (Jilin) Co. Ltd. (Baishan, China).
"Anti-CD137 antibodies and method of treating colorectal cancer using them" was invented by Xin Zhang (Suzhou, China), Jianjian Peng (Suzhou, China), Kai Fu (Suzhou, China), Hui Ma (Suzhou, China), Xiaolong Pan (Suzhou, China), Shilong Fu (Suzhou, China), Shuli Ma (Suzhou, China) and Jian Ding (Suzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "An antibody may be capable of specifically binding CD137 or an antigen binding fragment thereof, wherein the light chain variable region and the heavy chain variable region have one or more mut...