US Patent Issued to SHANGHAI SPH RARE DISEASE PHARMACEUTICAL on Nov. 25 for "Application of thyroid hormones and its analogues in preparation of drugs for treating alpha-thalassemia" (Chinese Inventor)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,478,600, issued on Nov. 25, was assigned to SHANGHAI SPH RARE DISEASE PHARMACEUTICAL Co. LTD. (Shanghai).

"Application of thyroid hormones and its analogues in preparation of drugs for treating alpha-thalassemia" was invented by Hao Yuan (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an application of thyroid hormones and its analogues in preparation of drugs for treating alpha-thalassemia, especially in preparation of drugs for regulating expression of zeta-globin gene. During differentiation of K562 cells, thyroid hormone analogue (Triac) can significantly up-regulate the expression of zeta-globin gene (HBZ) by...