ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,748, issued on June 10, was assigned to Shandong Boan Biotechnology Co. Ltd. (Yantai, China).

"Bifunctional fusion protein against PDL1 and TGFBeta and use thereof" was invented by Deyong Song (Yantai, China), Hongguang Xu (Yantai, China) and Zhen Han (Yantai, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are an anti-PDL1 antibody and an antigen-binding fragment thereof, and further provided are a bifunctional fusion protein against PDL1 and TGFBeta and a preparation method thereof and the use thereof. The antibody or antigen-binding fragment or the bifunctional fusion protein has one or more of the following advantages: an enhanced ...