ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,728, issued on July 15, was assigned to SERNOVA BIOTHERAPEUTICS INC. (London, Canada).
"Conformal coating of cells for immunoisolation" was invented by Jeffrey Hubbell (Preverenges, Switzerland) and Alice Tomei (Miami).
According to the abstract* released by the U.S. Patent & Trademark Office: "Hydrodynamic methods for conformally coating non -uniform size cells and cell clusters for implantation, thus preventing immune rejection or inflammation or autoimmune destruction while preserving cell functionality. A method for conformally coating cells and c clusters with hydrogels that are biocompatible, mechanically and chemically stable and porous, with an appropriate pore cut-off si...