ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,460,177, issued on Nov. 4, was assigned to SEOUL NATIONAL UNIVERSITY HOSPITAL (Seoul, South Korea).
"Composition for promoting efficiency of somatic cell replication" was invented by Eun Ju Lee (Seoul, South Korea) and Hyo-Soo Kim (Seoul, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a composition for promoting the efficiency of somatic cell replication, comprising endothelin as an active ingredient. When somatic cells are treated with the composition of the present invention, H3K9me3, which is suspected to be a factor for the lowering success rate of nuclear substitution, is inhibited, and H3K4me3, which has...