US Patent Issued to Seattle Children's Hospital, University of Washington on March 25 for "Production of engineered T-cells by sleeping beauty transposon coupled with methotrexate selection" (Washington Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,397, issued on March 25, was assigned to Seattle Children's Hospital (Seattle) and University of Washington (Seattle).

"Production of engineered T-cells by sleeping beauty transposon coupled with methotrexate selection" was invented by Michael C. Jensen (Bainbridge Island, Wash.), Suzie Pun (Seattle) and Nataly Kacherovsky (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the invention described herein include methods of treating, inhibiting, ameliorating and/or eliminating a virus or cancer cells in a subject utilizing genetically engineered human T-cells having receptors for a molecule presented by the virus or the cancer cells, ...