US Patent Issued to SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE on June 3 for "Agonists of the apelin receptor and methods of use thereof" (California, Florida Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,684, issued on June 3, was assigned to SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, Calif.).

"Agonists of the apelin receptor and methods of use thereof" was invented by Anthony B. Pinkerton (Rancho Santa Fe, Calif.) and Layton H. Smith (Orlando, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are small molecule agonists of the apelin receptor for the treatment of disease. The compounds disclosed herein are useful for the treatment of a range of cardiovascular, renal and metabolic conditions. The present invention is based on the seminal discovery of a series of potent small molecule agonists of the apelin recepto...