US Patent Issued to Sanford Burnham Prebys Medical Discovery Institute, Technion Research & Development Foundation on June 17 for "Gut microbiota and treatment of cancer" (American, Israeli Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,784, issued on June 17, was assigned to Sanford Burnham Prebys Medical Discovery Institute (La Jolla, Calif.) and Technion Research & Development Foundation Ltd. (Haifa, Israel).

"Gut microbiota and treatment of cancer" was invented by Yan Li (La Jolla, Calif.), Scott Peterson (La Jolla, Calif.), Linda Bradley (La Jolla, Calif.), Roberto Tinoco (La Jolla, Calif.), Ze'ev Ronai (San Diego) and Shiri Ashkenazi (Haifa, Israel).

According to the abstract* released by the U.S. Patent & Trademark Office: "The ubiquitin ligase, RNF5, regulates the gut microbiota composition and influences the immune checkpoint response to tumors. RNF5 deficient animals exhibit significant inhibition of t...