US Patent Issued to Research Institute at Nationwide Children's Hospital on Sept. 23 for "DNABII vaccines and antibodies with enhanced activity" (Ohio Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,419,944, issued on Sept. 23, was assigned to Research Institute at Nationwide Children's Hospital (Columbus, Ohio).

"DNABII vaccines and antibodies with enhanced activity" was invented by Lauren O. Bakaletz (Hilliard, Ohio) and Steven D. Goodman (Hilliard, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides methods and compositions that are useful to lessen and/or cure bacterial biofilms and treat diseases or disorders associated with biofilms using one or more novel polypeptide vaccines, antibodies, antibody fragments and compositions. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of th...