US Patent Issued to Research Institute at Nationwide Children's Hospital on Nov. 25 for "Syncytial oncolytic herpes simplex mutants as potent cancer therapeutics" (Ohio Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,480,097, issued on Nov. 25, was assigned to Research Institute at Nationwide Children's Hospital (Columbus, Ohio).

"Syncytial oncolytic herpes simplex mutants as potent cancer therapeutics" was invented by Timothy P. Cripe (Columbus, Ohio), Kevin A. Cassady (Columbus, Ohio), Pin-Yi Wang (Columbus, Ohio) and Julia K. Halley (Columbus, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides a non-natural herpes simplex virus ("HSV"), compositions comprising, or alternatively consisting essentially of, or yet further consisting of the HSV, and methods of producing the HSV, or infecting a cell with the HSV. Also provided herein are metho...