US Patent Issued to RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL, THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK on April 15 for "Products and methods for inhibition of expression of dynamin-1 variants" (New York, Ohio Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,941, issued on April 15, was assigned to RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) and THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York).

"Products and methods for inhibition of expression of dynamin-1 variants" was invented by Scott Quenton Harper (Powell, Ohio) and Wayne N. Frankel (Katonah, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "RNA interference-based methods and products for inhibiting the expression of pathogenic dynamin-1 variants are provided. Delivery vehicles such as recombinant adeno-associated viruses deliver DNAs encoding RNAs that inhibit the expression of the dynamin-1 varian...