US Patent Issued to REGENERON PHARMACEUTICALS on March 18 for "Genetically modified mouse with a humanized PNPLA3 gene and methods of use" (New York, New Jersey Inventors)

ALEXANDRIA, Va., March 19 -- United States Patent no. 12,250,931, issued on March 18, was assigned to REGENERON PHARMACEUTICALS INC. (Tarrytown, N.Y.).

"Genetically modified mouse with a humanized PNPLA3 gene and methods of use" was invented by Xiping Cheng (Northvale, N.J.), Jose F. Rojas (Newburgh, N.Y.) and Mark Sleeman (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Non-human animal genomes, non-human animal cells, and non-human animals comprising a humanized PNPLA3 locus and methods of making and using such non-human animal genomes, non-human animal cells, and non-human animals are provided. Non-human animal cells or non-human animals comprising a humanized PNPLA3 locus express a human PNPLA3 p...