ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,290, issued on March 25, was assigned to REALTA HOLDINGS LLC (Norfolk, Va.).
"PIC1 inhibition of myeloperoxidase oxidative activity in an animal model" was invented by Neel K. Krishna (Norfolk, Va.) and Kenji Cunnion (Norfolk, Va.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of treating systemic lupus erythematosus in a subject is provided in which a therapeutically effective amount of PIC1 is administered to the subject. A method of treating transfusion-related acute lung injury is also provided where a therapeutically effective amount of PIC1 is administered to the subject. PIC1 can modulate immune complex activation of the complement ...