ALEXANDRIA, Va., June 12 -- United States Patent no. 12,300,356, issued on May 13, was assigned to QUEEN'S UNIVERSITY AT KINGSTON (Kingston, Canada), INSTITUT CURIE (Paris) and INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (Paris).
"Cell-free detection of methylated tumour DNA" was invented by Christopher R. Mueller (Kingston, Canada) and Marc-Henri Stern (Paris).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a method for detecting a tumour that can be applied to cell-free samples, e.g., to cell-free detect circulating tumour DNA. The method utilizes detection of adjacent methylation signals within a single sequencing read as the basic positive tumour signal, thereby de...