US Patent Issued to Pyramid Biosciences on Dec. 2 for "5-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-(1H-pyrazol-1-yl)pyrazolo[1,5-apyrimidine derivatives and related compounds as Trk kinase inhibitors for treating cancer" (Canadian, American Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,276, issued on Dec. 2, was assigned to Pyramid Biosciences Inc. (Waltham, Mass.).

"5-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-(1H-pyrazol-1-yl)pyrazolo[1,5-apyrimidine derivatives and related compounds as Trk kinase inhibitors for treating cancer" was invented by Kollol Pal (Needham, Mass.), Stephane Ciblat (Montreal), Vincent Albert (Rigaud, Canada), Nicolas Bruneau-Latour (Pointe-Fortune, Canada) and Jonathan Boudreault (L'lle-Perrot, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The application relates to pyrazolo[1,5-a]pyrimidine derivatives of formula (IV) as Trk kinase inhibitors for treating cancer and inflammatory diseases."

The patent...