ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,469,688, issued on Nov. 11, was assigned to Purdue Research Foundation (West Lafayette, Ind.).

"Reaction monitoring" was invented by Robert Graham Cooks (West Lafayette, Ind.), Xin Yan (West Lafayette, Ind.), Christopher Pulliam (West Lafayette, Ind.), Ryan M. Bain (West Lafayette, Ind.) and Tawnya Flick (Thousand Oaks, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention generally relates to systems and methods for on-line reaction monitoring. In certain embodiments, the invention provides systems that include a reaction vessel having an outlet, a quantitation unit coupled to the outlet and configured to introduce internal standard and s...