US Patent Issued to Purdue Research Foundation on Aug. 26 for "Compounds and methods for the treatment and prevention of fibrotic disease states and cancer" (Indiana Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,397,059, issued on Aug. 26, was assigned to Purdue Research Foundation (West Lafayette, Ind.).

"Compounds and methods for the treatment and prevention of fibrotic disease states and cancer" was invented by Philip Stewart Low (West Lafayette, Ind.), Fenghua Zhang (West Lafayette, Ind.) and John Victor Napoleon (West Lafayette, Ind.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds, pharmaceutical compositions and methods are provided for reprogramming M2-like macrophages to M1-like macrophages, which reverses the antifibrotic to profibrotic shift observed during the course of fibrotic diseases and certain cancers. The compounds comprise an immune ...