US Patent Issued to President and Fellows of Harvard College on Oct. 28 for "Method of reducing glucose intolerance or insulin resistance in a patient in need thereof" (Massachusetts, Maryland Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,569, issued on Oct. 28, was assigned to President and Fellows of Harvard College (Cambridge, Mass.).

"Method of reducing glucose intolerance or insulin resistance in a patient in need thereof" was invented by Gokhan S. Hotamisligil (Wellesley, Mass.) and Haiming Cao (Bethesda, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of reducing a symptom of a clinical disorder characterized by aberrantly elevated circulating aP2 is carried out by administering to a subject an inhibitor of secreted aP2, secretion of aP2, or a serum aP2 blocking agent. For example, glucose intolerance is reduced following administration of such an inhibitor or agen...