US Patent Issued to President and Fellows of Harvard College, Dana-Farber Cancer Institute on Dec. 2 for "In situ gene editing" (Massachusetts, California Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,519, issued on Dec. 2, was assigned to President and Fellows of Harvard College (Cambridge, Mass.) and Dana-Farber Cancer Institute Inc. (Boston).

"In situ gene editing" was invented by Amy J. Wagers (Cambridge, Mass.), Jill Goldstein (Cambridge, Mass.), Leo Wang (La Canada Flintridge, Calif.), Ya-Chieh Hsu (Cambridge, Mass.) and Meryem Gonzalez Celeiro (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are methods of in situ genomic modification of cells (e.g., stem cells, tissue stem cells, muscle stem cells, Sca-1+ mesenchymal progenitor cells in skeletal muscle, CD140a+ dermal mesenchymal cells) using sequence-targeting n...