US Patent Issued to Prelude Therapeutics on Nov. 4 for "Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)" (American, Spanish Inventors)

ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,459,950, issued on Nov. 4, was assigned to Prelude Therapeutics Inc. (Wilmington, Del.).

"Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)" was invented by Juan Luengo (Phoenixville, Pa.), Hong Lin (Exton, Pa.), Michael Hawkins (Ambler, Pa.), Rupa Shetty (Blue Bell, Pa.), Philip Pitis (North Wales, Pa.) and Gisela Saborit Villarroya (Barcelona, Spain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure is directed to compounds of Formula IPharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described."

The patent was filed on Feb. 17, 2022, under Application...