ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,448, issued on Feb. 17, was assigned to Pharmacyclics LLC (North Chicago, Ill.).
"Pharmaceutical formulations of a Bruton's tyrosine kinase inhibitor" was invented by Ching Wah Chong (Fremont, Calif.), Robert Kuehl (San Francisco), Heow Tan (Cupertino, Calif.) and Harisha Atluri (Palo Alto, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are pharmaceutical formulations of Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one. Also disclosed are methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for t...