US Patent Issued to Pharmacosmos Holding on May 27 for "Substituted 1',2'-dihydro-3'H-spiro[cyclohexane-1,4'-pyrimido[5',4':4,5pyrrolo[2,1-c[1,2,4triazin-3'-ones as cyclin-dependent kinase inhibitors" (North Carolina Inventor)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,360, issued on May 27, was assigned to Pharmacosmos Holding A/S (Holbaek, Denmark).

"Substituted 1',2'-dihydro-3'H-spiro[cyclohexane-1,4'-pyrimido[5',4':4,5pyrrolo[2,1-c[1,2,4triazin-3'-ones as cyclin-dependent kinase inhibitors" was invented by Jay Copeland Strum (Hillsborough, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention is in the area of cell cycle inhibiting compounds for the treatment of disorders involving abnormal cellular proliferation, and include selective CDK2 inhibitors for medical therapy and their pharmaceutically acceptable salts and compositions. The inhibitors are pyrimidine-based N-heterocyclic compounds of fo...