ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,129, issued on Aug. 26, was assigned to PERHA PHARMACEUTICALS (Roscoff, France).

"Imidazolone derivatives as inhibitors of protein kinases in particular DYRK1A, CLK1 and/or CLK4" was invented by Emmanuel Deau (Roscoff, France), Pascal George (Roscoff, France), Laurent Meijer (Roscoff, France) and Frederic Miege (Lyons, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a compound of formula (I) wherein R1 represents a (C1-C6)alkyl group, a spiro(C5-C11)bicyclic ring, a fused phenyl group, a substituted phenyl group, a R'-L- group, wherein L is either a single bond or a (C1-C3)alkanediyl group, and R' represents a ...