US Patent Issued to Paul G. Richardson on Jan. 20 for "Defibrotide for the prevention and treatment of cytokine release syndrome and neurotoxicity associated with immunodepletion" (California Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,527,811, issued on Jan. 20, was assigned to Paul G. Richardson (Wellesley, Mass.).

"Defibrotide for the prevention and treatment of cytokine release syndrome and neurotoxicity associated with immunodepletion" was invented by Sarah McMahon (Palo Alto, Calif.) and Yasuhiro Oki (Palo Alto, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides method of preventing, lessening the effects, or treating cytokine release syndrome (CRS) or related disorders, and/or neurotoxicity associated with immunotherapy comprising administering defibrotide. The defibrotide can be administered after the immunotherapy begins or be administered p...