US Patent Issued to Ospedale San Raffaele, Istituto Nazionale Genetica Molecolare-INGM on Sept. 2 for "Spirocyclic inhibitors of hepatitis B virus" (Italian Inventors)

ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,284, issued on Sept. 2, was assigned to Ospedale San Raffaele S.r.l. (Milan) and Istituto Nazionale Genetica Molecolare-INGM (Milan).

"Spirocyclic inhibitors of hepatitis B virus" was invented by Romano Di Fabio (Pomezia, Italy), Vincenzo Summa (Pomezia, Italy), Leda Ivanova Bencheva (Milan), Raffaele De Francesco (Milan), Lorena Donnici (Milan), Luca Guidotti (Milan), Matteo Iannacone (Milan), Adolfo Prandi (Milan), Marilenia De Matteo (Milan) and Pietro Randazzo (Milan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compounds that are inhibitors of hepatitis B virus (HBV). Compounds of this invention are useful alon...