ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,375, issued on Oct. 21, was assigned to Ohio State Innovation Foundation (Columbus, Ohio) and Reaction Biology Corp. (Malvern, Pa.).

"Kinase inhibitors for the treatment of neurodegenerative diseases" was invented by Yangbo Feng (Malvern, Pa.) and Sung Ok Yoon (Columbus, Ohio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compounds that are kinase inhibitors. The compounds have improved properties that lead to specific targeting of kinases without inhibiting the activity of related enzymes, which make them useful for therapeutic intervention in a variety of disorders and disease in which inhibition of the kinase can be clinically useful...